Metronomic Chemotherapy: Pharmacology and Clinical Applications 2014th Edition

Ebook Details


Guido Bocci, Giulio Francia

Year 2014
Pages 295
Publisher Springer
Language en
ISBN 9783662436035
File Size 2.7 MB
File Format PDF
Download Counter 100
Amazon Link

Ebook Description

This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.