Signaling in the Heart 2011th Edition

Ebook Details

Authors

José Marín-García

Year 2011
Pages 507
Publisher Springer
Language en
ISBN 9781441994608
File Size 14.13 MB
File Format PDF
Download Counter 109
Amazon Link

Ebook Description

Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology.  The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome.  Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact.