This book investigates the modeling and optimization issues in mobile social networks (MSNs). Firstly, the architecture and applications of MSNs are examined. The existing works on MSNs are reviewed by specifying the critical challenges and research issues. Then, with the introduction of MSN-based social graph and information dissemination mechanisms, the analytical model for epidemic information dissemination with opportunistic Links in MSNs is discussed. In addition, optimal resource allocation is studied based on a heterogeneous architecture, which provides mobile social services with high capacity and low latency. Finally, this book summarize some open problems and future research directions in MSNs.